I’ve been reading about an archaeological trek into remote Honduran jungle in search of a legendary ancient city. It was quite an amazing adventure, an Indiana Jones-like quest complete with impenetrable jungle, deadly snakes and swarms of biting insects. Upon the adventurers return to civilization several of them were found to have contracted a devastating disease: sand fly bites had introduced into their blood streams a most insidious parasite.
Due to the variety of mutations the tiny invaders assume, medical researchers were (and still are) hard pressed to even begin to eradicate the disease. No treatment now available will rid an infected body of the parasite completely, meaning, I guess, that one must play host to the uninvited community of little blood swimmers in perpetuity.
The reality of the situation rather takes the romance out of it all for us armchair adventurers: I suppose National Geographic will have to suffice.